What is polycystic ovary syndrome and how does it affect fertility?
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The Synevo Team
October 6 2022
A recent paper published in Science reports that viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain modern viruses. The researchers have scanned the human genome and uncovered many sequences with potential antiretroviral activity. Read more about this study under Article 1.
This paper reports that viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain modern viruses. Previous studies have shown that fragments of ancient viral DNA, called endogenous retroviruses encoding envelope proteins, in the genomes of several mammals provide immunity against modern viruses by blocking them from entering host cells. The researchers have scanned the human genome and uncovered many envelope-derived sequences with potential antiretroviral activity. They found that one envelope-derived protein called Suppressyn, which is expressed in the developing placenta and is capable of binding to a receptor for a wide number of retroviruses, could restrict infection by extant mammalian type D retroviruses. The team speculates that Suppressyn may have been preserved in the human genome for its ability to shield the early embryo and nascent germline from infection. Read the full article here: https://www.science.org/doi/10.1126/science.abq7871
In summary: Ancient viral DNA in human genome guards against infections
This protein atlas graphic was assembled during the summer of 2022 based on the most current papers, preprints, and feedback from scientists. This atlas visualizes the latest SARS-CoV-2 information, including protein structures. However, as SARS-CoV-2 information continues to rapidly change, some information may therefore be out of date. Some protein structures were not fully available and were therefore predicted using either homology modeling, de novo modeling, artificial intelligence prediction, or inferred artistically based on similar molecules/other known structures. Enjoy scrolling through the atlas! Read the full article here: https://www.science.org/content/article/how-sars-cov-2-battles-our-immune-system
In summary: The protein arsenal wielded by SARS-CoV-2